Publicaciones
cronobiologia cronobiology golombek ritmos rythms circadian timing time
 






 

2013:
• Paladino N, Duhart JM, Mul Fedele ML, Golombek DA. Characterization of locomotor activity circadian rhythms in athymic nude mice. J Circadian Rhythms. 2013 Feb 1;11(1):2.

2012:
• Leone MJ, Marpegan L, Duhart JM, Golombek DA. Role of proinflammatory cytokines on lipopolysaccharide-induced phase shifts in locomotor activity circadian rhythm. Chronobiol Int. 2012 Jul;29(6):715-23.

• Plano SA, Agostino PV, de la Iglesia HO, Golombek DA. cGMP-phosphodiesterase inhibition enhances photic responses and synchronization of the biological circadian clock in rodents. PLoS One. 2012;7(5):e37121.

Katz ME, Margulis F, Schiavelli R, Arias P, Head GA, Golombek DA. Disruption of Transitional Stages in 24-h Blood Pressure Recording in Renal Transplant Recipients. Front Neurol. 2012;3:35. doi: 10.3389/fneur.2012.00035. Epub 2012 Mar 16.

Casiraghi LP, Oda GA, Chiesa JJ, Friesen WO, Golombek DA. Forced desynchronization of activity rhythms in a model of chronic jet lag in mice. J Biol Rhythms. 2012 Feb;27(1):59-69.

Agostino PV, Golombek DA, Meck WH. Unwinding the molecular basis of interval and circadian timing. Front Integr Neurosci. 2011;5:64.

Migliori ML, Romanowski A, Simonetta SH, Valdez D, Guido M, Golombek DA. Daily variation in melatonin synthesis and arylalkylamine N-acetyltransferase activity in the nematode Caenorhabditis elegans. J Pineal Res. 2012 Aug;53(1):38-46.

2011:
• Migliori ML, Simonetta SH, Romanowski A, Golombek DA. Circadian rhythms in metabolic variables in Caenorhabditis elegans. Physiol Behav. 2011 Jun 1;103(3-4):315-20.

Agostino PV, do Nascimento M, Bussi IL, Eguía MC, Golombek DA. Circadian modulation of interval timing in mice. Brain Res. 2011 Jan 25;1370:154-63.

• Romanowski A, Migliori ML, Valverde C, Golombek DA. Circadian variation in Pseudomonas fluorescens (CHA0)-mediated paralysis of Caenorhabditis elegans. Microb Pathog. 2011 Jan;50(1):23-30.

2010:
• Golombek DA, Rosenstein RE. Physiology of circadian entrainment. Physiol Rev. 2010 Jul;90(3):1063-102. doi: 10.1152/physrev.00009.2009. Review.

• Paladino N, Leone MJ, Plano SA, Golombek DA. Paying the circadian toll: the circadian response to LPS injection is dependent on the Toll-like receptor 4. J Neuroimmunol. 2010 Aug 25;225(1-2):62-7.

• Casiraghi LP, Croci DO, Poirier F, Rabinovich GA, Golombek DA. "Time sweet time": circadian characterization of galectin-1 null mice. J Circadian Rhythms. 2010 Apr 19;8:4.

• Plano SA, Golombek DA, Chiesa JJ. Circadian entrainment to light-dark cycles involves extracellular nitric oxide communication within the suprachiasmatic nuclei. Eur J Neurosci. 2010 Mar;31(5):876-82.

• Casiraghi L; Martino D; Marengo E; Igoa A; Ais E; Strejilevich S; Golombek D. Human period-3 gene is involved in diurnal preference in an Argentinean population of bipolar disorders patients. Sleep Science, 3(1):22-27.

2009:
• Agostino PV, Harrington ME, Ralph MR, Golombek DA. Casein kinase I-epsilon and circadian photic entrainment in hamsters. Chronobiol Int 26(1): 1-8, 2009.
• Cardinali DP; Golombek DA. Let there be sleep – on time. Lancet 373: 439-440, 2009.
• Marpegan L; Leone MJ; Katz ME; Sobrero PM; Golombek DA. Diurnal rhythm in endotoxin-induced mortality in mice: correlation with proinflammatory factors and lack of circadian variation. Chronobiology International 26(7):1430-1442, 2009.
• Simonetta SH; Migliori ML; Romanowski A; Golombek DA. Timing of locomotor activity circadian rhythms in Caenorhabditis elegans. PLoS ONE 4(10):e7571. 2009.

2008:
• Pizzio GA, Golombek DA. Photic regulation of MAP kinase phosphatases MKP1/2 and MKP3 in the hamster suprachiasmatic nuclei. J Molec Neurosci, 34(2):187-92, 2008.
• Katz ME, Simonetta SH, Ralph MR, Golombek DA. Immunosuppressant calcineurin inhibitors phase shift circadian rhythms and inhibit circadian responses to light. Pharmacol Biochem Behav 90: 763-768, 2008.
• Simonetta SH, Romanowski A, Minitti AN, Inestrosa NC, Golombek DA. Circadian stress resistance in C. elegans. J Comp Physiol A 194 (9): 821-828, 2008.
• Agostino PV, Plano SA, Golombek DA. Circadian and pharmacological regulation of casein kinase I in the hamster SCN. J Genetics 87(5): 467-471, 2008.

2007:
• Simonetta, SH; Golombek DA. An automated tracking system for C. elegans locomotor behavior and circadian studies application. J Neurosci Methods, 161(3): 273-280, 2007.
• Agostino PA; Plano SA; Golombek DA. Sildenafil accelerates reentrainment of circadian rhythms. Proc Nat Aca Sci (USA), 104(23): 9834-9839, 2007.
• Yannielli PC; Molyneux P; Harrington ME; Golombek DA. Ghrelin effects on the circadian system of mice. J Neurosci 27(11): 2890-2895, 2007.
• Leone MJ, Marpegan L; Chiesa JJ; Golombek DA. A time to kill and a time to heal. Pathophysiological interactions between the circadian and the immune systems. Physiological Minireviews 2 (10): 60-69, 2007.
• Plano SA, Agostino PV, Golombek DG. Extracellular nitric oxide signalling in the mammalian circadian system. FEBS Letters 581: 5500–5504, 2007.

2006:
• Leone MJ, Marpegan L, Bekinschtein T, Costas MC, Golombek DA. Suprachiasmatic astrocytes as an interphase for immune-circadian signalling. J Neurosci Res, 84: 1521-1527, 2006.
• Hainich EC; Pizzio GA; Golombek DA. Constitutive activation of the ERK-MAPK pathway in the suprachiasmatic nuclei inhibits circadian resetting. FEBS Letters, 580: 6665-668, 2006.

2005:
• Marpegan, L.; Bekinschtein, T.; Costas, M.R.; Golombek, D.A. Effects of LPS on the circadian system. J Neuroimmunol, 160(1-2):102-9, 2005.
• Pizzio GA, Hainich EC, Plano, SA, Ralph MR, Golombek DA. Nerve growth factor-induced circadian phase shifts and MAP kinase activation in the hamster SCN. Eur J Neurosci 22(3): 665-671, 2005.

2004:
• Agostino, P., Ferreyra, G.; Murad, A.; Watanabe, Y; Golombek, D. Diurnal, circadian and photic regulation of calcium/calmodulin-dependent kinase II and neuronal nitric oxide synthase in the hamster suprachiasmatic nuclei. Neurochem Int 44(8):617-25, 2004.
• Golombek DA, Agostino PV, Plano SA, Ferreyra GA. Signaling in the mammalian circadian clock: the NO/cGMP pathway. Neurochem Int. 45(6):929-36, 2004.
• Marpegan, L.; Freudenthal, R.; Ferreyra, G.; Romano, A.; Golombek, D. Participation of transcription factors from the Rel/A-NFkB family in the circadian system. Neurosci Lett, 358(1):9-12, 2004.
• Bekinschtein, T.A.; Negro, A.; Goldín, A.; Fernández, M.P.; Rosenbaum, S. and Golombek, D.A. Seasonality in a Mapuche native population. Biol Rhythms Res 35 (1-2): 145-152, 2004.

2003:
• Agostino, P.; Grilli, L.; Golombek, D. Characterization of suprachiasmatic nuclei proteases. Biol Rhythm Res 33(4); 383-390, 2003.
• Pizzio, G.A.; Hainich, E.C.; Ferreyra, G.A.; Coso, O.A.; Golombek, D.A. Circadian and photic regulation of three major MAP kinase cascades in the hamster SCN. Neuroreport 14(11): 1417-1419, 2003.
• Golombek, D.A.; Ferreyra, G.A.; Agostino, P.A.; Murad, A.D.; Rubio, M.G.; Pizzio, G.A.; Katz, M.E.; Marpegan L.; Bekinschtein, T.A. From light to genes: Moving the hands of the circadian clock. Front Biosci, 8: S285-93, 2003.
• Naum, G.; Golombek, D. Time-dependent etomidate anesthesia in hamsters. Biol Rhythm Res 33(4): 437-442, 2003.
• Rubio, M.F.; Agostino, P.V.; Ferreyra, G.A.; Golombek, D.A. Circadian heme oxygenase activity in the hamster suprachiasmatic nuclei. Neurosci Lett 353(1):9-12, 2003.

2002:
• Naum, G.; Cardozo, J.; Golombek, D. Daily variation in the proconvulsant effect of 3-mercaptopropionic acid and the anticonvulsant effect of androsterone in the Syrian hamster. Life Sci 71: 91-98, 2002.

2001:
• Ferreyra, G.; Golombek, D. Rhythmicity of the cGMP-related function in the circadian system. Am J Physiol 280(5):R1348-55, 2001.
• Lema, M.; Echave, J.; Golombek, D. Too many mathematical models of circadian rhythms? Biol Rhythm Res 32(2): 285-298, 2001.
• Naum, G.; Rubio, F.; Golombek, D. Rhythmic variation in GABA A-receptor subunit composition in the circadian system and median eminence of Syrian hamsters. Neurosci Lett 310(2-3):178-182, 2001.

2000:
• Golombek, D.; Ferreyra, G.; Katz, M.; Marpegan, L.; Fernández, T.; Yannielli, P. The neurochemical basis of photic entrainment in mammals. Biol Rhythm Res 31: 56-70, 2000.
• Yannielli, P.; Kargieman, L.; Gregoretti, L.; Cadeiras, M.; Golombek, D. Acute, chronic and neonatal clomipramine and the circadian system of hamsters. Biol Rhythm Res, 31: 391-415, 2000.
• Ferreyra, G.; Golombek, D. cAMP-dependent protein kinase activity in the suprachiasmatic nuclei. Brain Res, 858: 33-39, 2000.

1998:
• Ferreyra, G.; Cammarota, M.; Golombek, D. Photic control of nitric oxide synthase activity in the suprachiasmatic nuclei. Brain Res 797 (2): 190-196, 1998.
• Golombek, D.; Yannielli, P.; Cardinali, D. Reentrainment in hamsters: effect of age, melatonin and neonatal clomipramine treatment. Biol Rhythms Res 29 (5): 501-509, 1998.
• Yannielli, P.; Cutrera, R.; Cardinali, D.; Golombek, D. Neonatal clomipramine treatment in golden hamsters: effects on the circadian system. Eur J Pharmacol 349: 143-150, 1998.
• Yannielli, P.; Cadeiras, M.; Cardinali, D.; Golombek, D. Effects of acute clomipramine administration on the hamster circadian system. Biol Rhythm Res 29 (5): 530-537, 1998.


PATENTES

• Simonetta, S.; Golombek, D. Procedimiento y dispositivo de registro locomotor de organismos pequeños y registro comportamental obtenido. Autores: CONICET – Universidad Nacional de Quilmes. Presentado en junio de 2006.
• Golombek, D.; Agostino, P.; Plano, S., Ferreyra, G. Use of PDE5 inhibitors for treating circadian rhythm disorders. USPTO Filing Serial # 60967567, September 5, 2007.